(S)-1-苯基-3-丁烯-1-醇合成路线 （共 84 条）
反应条件
pyridinium bromide perbromide in methanol
T=0°C;
参考文献
Martinez-Solorio, Dionicio; Jennings, Michael P.
Tetrahedron Letters, 2008 , vol. 49, # 35 p. 5175 - 5178
反应条件
pyridinium bromide perbromide in methanol
T=0°C;
参考文献
Martinez-Solorio, Dionicio; Jennings, Michael P.
Tetrahedron Letters, 2008 , vol. 49, # 35 p. 5175 - 5178
反应条件
in diethyl ether
T=-100°C; 1 h; Title compound not separated from byproducts;
参考文献
Felpin, Francois-Xavier; Lebreton, Jacques
Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9192 - 9199
反应条件
chromium dichloride; triethylamine; chloro-trimethyl-silane in tetrahydrofuran
T=20°C; Nozaki-Hiyama reaction; 20 h; Title compound not separated from byproducts;
参考文献
Lee, Jae-Young; Miller, Jeremie J.; Hamilton, Steven S.; Sigman, Matthew S.
Organic Letters, 2005 , vol. 7, # 9 p. 1837 - 1839
反应条件
triethyl borane; (R)-1,1'-spirobiindan-7,7'-diyldimethyl=P-Ph; palladium diacetate in tetrahydrofuran; hexane
T=25°C; 24 h; Title compound not separated from byproducts;
参考文献
Zhu, Shou-Fei; Yang, Yun; Wang, Li-Xin; Liu, Bin; Zhou, Qi-Lin
Organic Letters, 2005 , vol. 7, # 12 p. 2333 - 2335
反应条件
1: With scandium tris(trifluoromethanesulfonate) in dichloromethane
T=-78°C; 16 h;
2: With diisobutylaluminium hydride in dichloromethane; toluene
T=-78°C; 0.5 h; Title compound not separated from byproducts;
参考文献
Lachance, Hugo; Lu, Xiaosong; Gravel, Michel; Hall, Dennis G.
Journal of the American Chemical Society, 2003 , vol. 125, # 34 p. 10160 - 10161
反应条件
(i-C3H7)SB(C2H5)2; (S)-BINOL-Ti(O-i-Pr)4 in dichloromethane
T=-20°C; various quantities of complex; other reagent; Product distribution;
参考文献
Yu, Chan-Mo; Choi, Ha-Soon; Jung, Won-Hyuk; Kim, Hyuk-Jun; Shin, Jaewook
Chemical Communications, 1997 , # 8 p. 761 - 762
反应条件
1: 3-chloroprop-1-ene With chromium dichloride; H2Salen; triethylamine in acetonitrile
T=20°C; Metallation;
2: benzaldehyde With chloro-trimethyl-silane in acetonitrile
Addition;
参考文献
Bandini, Marco; Cozzi, Pier Giorgio; Melchiorre, Paolo; Umani-Ronchi, Achille
Angewandte Chemie - International Edition, 1999 , vol. 38, # 22 p. 3357 - 3359
反应条件
1: tetravinyl tin With methyllithium in tetrahydrofuran; diethyl ether
T=0°C; 1 h;
2: in tetrahydrofuran; diethyl ether
T=-78 - -30°C;
3: (R)-2-phenyloxirane in tetrahydrofuran; diethyl ether
T=-30 - 20°C; Further stages.;
参考文献
Kang, Byungman; Chang, Sukbok
Tetrahedron, 2004 , vol. 60, # 34 p. 7353 - 7359
反应条件
Candida antarctica lipase B; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; sodium carbonate in tetrahydrofuran; toluene
T=70°C; 12 h; Schlenk techniqueInert atmosphereResolution of racemateEnzymatic reaction; TemperatureTimeReagent/catalyst; enantioselective reaction;
参考文献
Warner, Madeleine C.; Shevchenko, Grigory A.; Jouda, Suzan; Bogar, Krisztian; Baeckvall, Jan-E.
Chemistry - A European Journal, 2013 , vol. 19, # 41 p. 13859 - 13864
