(S)-1-苯基-3-丁烯-1-醇合成路线 （共 84 条）
反应条件
in diethyl ether
Yield given. Yields of byproduct given;
参考文献
Schmidt, Beat; Seebach, Dieter
Angewandte Chemie, 1991 , vol. 103, # 1 p. 100 - 101
反应条件
molecular sieve; lipase B from Candida antarctica in 1,4-dioxane
T=30°C; 163 h; Title compound not separated from byproducts;
参考文献
Garcia-Urdiales, Eduardo; Rebolledo, Francisca; Gotor, Vicente
Tetrahedron Asymmetry, 2001 , vol. 12, # 21 p. 3047 - 3052
反应条件
1: in diethyl ether
T=-78°C; 2 h;
2: With hydrogenchloride in diethyl ether
T=20°C;
参考文献
Thormeier, Sabine; Carboni, Bertrand; Kaufmann, Dieter E
Journal of Organometallic Chemistry, 2002 , vol. 657, # 1-2 p. 136 - 145
反应条件
chloro-trimethyl-silane; C2-symmetrical tridentate bis(oxazolinyl)carbazole-Cr(III); triethylamine in tetrahydrofuran
T=20°C; 1 h; Title compound not separated from byproducts;
参考文献
Suzuki, Takahiro; Kinoshita, Akihiro; Kawada, Hatsuo; Nakada, Masahisa
Synlett, 2003 , # 4 p. 570 - 572
反应条件
(-)-10-CSA in dichloromethane
T=15°C; 164 h;
参考文献
Lee, Cheng-Hsia Angeline; Loh, Teck-Peng
Tetrahedron Letters, 2004 , vol. 45, # 30 p. 5819 - 5822
反应条件
novozyme 435 in toluene
T=60°C; 6 h; microwave irradiation;
参考文献
Bachu, Prabhakar; Gibson, Jennifer S.; Sperry, Jonathan; Brimble, Margaret A.
Tetrahedron Asymmetry, 2007 , vol. 18, # 13 p. 1618 - 1624
反应条件
1: PCC
2: 1.) MCPBA, 2.) p-TSA*pyridine / 1.) CH2Cl2, room temperature, 2.) MeOH, 60 deg
View Scheme
参考文献
McNamara, J. M.; Kishi, Y.
Journal of the American Chemical Society, 1982 , vol. 104, # 25 p. 7371 - 7372
反应条件
4 A molecular sieve in toluene
T=-40°C; 40 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Zhang, Luo Cheng; Sakurai, Hideki; Kira, Mitsuo
Chemistry Letters, 1997 , # 2 p. 129 - 130
反应条件
L-prolinol; L-proline in dichloromethane
T=-78 - 20°C; 10 h; Molecular sieveInert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chen, Guo-Hong; Liu, Ling-Yan; Wei, Xiao-Ning; Chang, Wei-Xing; Li, Jing
Chemistry Letters, 2010 , vol. 39, # 9 p. 1013 - 1015
反应条件
amino lipase PS
T=20°C; 70 h; Enzymatic reaction; optical yield given as percent ee;
参考文献
Roesner, Stefan; Casatejada, Javier Mansilla; Elford, Tim G.; Sonawane, Ravindra P.; Aggarwal, Varinder K.
Organic Letters, 2011 , vol. 13, # 21 p. 5740 - 5743
