(S)-1-苯基-3-丁烯-1-醇合成路线 （共 84 条）
反应条件
sodium hydroxide; dihydrogen peroxide
1.) Et2O, -78 deg C, 3 h, 2.) reflux, 3 h; Multistep reaction. Title compound not separated from byproducts;
参考文献
Brown, Herbert C.; Randad, Ramnarayan S.; Bhat, Krishna S.; Zaidlewicz, Marek; Racherla, Uday S.
Journal of the American Chemical Society, 1990 , vol. 112, # 6 p. 2389 - 2392
反应条件
cyclopentadienyllt;(4R,trans)-2,2-dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanolato-O,O'gt;titanium chloride
1.) var. titanium complexes; enantioselective allyltitanation of aldehydes with cyclopentadienyldialkoxyallyltitanium complexes; Product distributionMechanism;
参考文献
Hafner, Andreas; Duthaler, Rudolf O.; Marti, Roger; Rihs, Grety; Rothe-Streit, Petra; Schwarzenbach, Franz
Journal of the American Chemical Society, 1992 , vol. 114, # 7 p. 2321 - 2336
反应条件
in toluene
72 h; Title compound not separated from byproducts.;
参考文献
Kinnaird, James W. A.; Ng, Pui Yee; Kubota, Katsumi; Wang, Xiaolun; Leighton, James L.
Journal of the American Chemical Society, 2002 , vol. 124, # 27 p. 7920 - 7921
反应条件
1: in tetrahydrofuran
T=-78°C; 0.666667 h;
2: With sodium tetrahydroborate in tetrahydrofuran; ethanol
T=-78 - 20°C; 1 h; Further stages. Title compound not separated from byproducts.;
参考文献
Vorontsova; Zhuravsky; Sergeeva; Vorontsov; Starikova; Rozenberg
Russian Chemical Bulletin, 2007 , vol. 56, # 11 p. 2225 - 2231
反应条件
scandium tris(trifluoromethanesulfonate) in dichloromethane
T=-78°C; 24 h; Title compound not separated from byproducts.;
参考文献
Friberg, Annika; Sarvary, Ian; Wendt, Ola F.; Frejd, Torbjoern
Tetrahedron Asymmetry, 2008 , vol. 19, # 15 p. 1765 - 1777
反应条件
L-prolinol; L-proline in dichloromethane
T=-78 - 20°C; 10 h; Molecular sieveInert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chen, Guo-Hong; Liu, Ling-Yan; Wei, Xiao-Ning; Chang, Wei-Xing; Li, Jing
Chemistry Letters, 2010 , vol. 39, # 9 p. 1013 - 1015
反应条件
L-prolinol; L-proline in dichloromethane
T=-78 - 20°C; 10 h; Molecular sieveInert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chen, Guo-Hong; Liu, Ling-Yan; Wei, Xiao-Ning; Chang, Wei-Xing; Li, Jing
Chemistry Letters, 2010 , vol. 39, # 9 p. 1013 - 1015
反应条件
tin(II) trifluoromethanesulfonate; (S)-1-methyl-2-lt;(piperidin-1-yl)-methylgt;pyrrolidine in dichloromethane
T=-78°C; 1 h; further conditions; further chiral diamines; Product distribution;
参考文献
Minowa, Nobuto; Mukaiyama, Teruaki
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 10 p. 3697 - 3704
反应条件
(dimethyl)chloroborane
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Brown, Herbert C.; Jadhav, Prabhakar K.
Journal of the American Chemical Society, 1983 , vol. 105, # 7 p. 2092 - 2098
反应条件
in hexane
6 h; Heating; Title compound not separated from byproducts;
参考文献
Canales, Eda; Prasad, K. Ganeshwar; Soderquist, John A.
Journal of the American Chemical Society, 2005 , vol. 127, # 33 p. 11572 - 11573
