(S)-1-苯基-3-丁烯-1-醇合成路线 （共 84 条）
反应条件
Yields of byproduct given;
参考文献
Bracher, Franz; Litz, Thomas
Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 6 p. 877 - 880
参考文献
Faraldos, Juan; Arroyo, Elisa; Herradon, Bernardo
Synlett, 1997 , vol. 1997, # 4 p. 367 - 370
反应条件
in toluene
T=-78°C; 16 h; Product distribution; Further Variations:SolventsTemperaturesReaction partners;
参考文献
Chen, Wansuo; Liu, Yanzhu; Chen, Zhirong
European Journal of Organic Chemistry, 2005 , # 8 p. 1665 - 1668
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / 1.25 h / 20 °C / Inert atmosphere
1.2: 24 h / Inert atmosphere; Reflux
2.1: sec.-butyllithium / diethyl ether; hexane; cyclohexane / 1 h / -78 °C / Inert atmosphere
2.2: 2 h / -78 °C / Inert atmosphere
3.1: cesium fluoride / dichloromethane; water / 16 h / 20 °C
4.1: tetrahydrofuran / 2 h / 20 °C
5.1: dihydrogen peroxide; sodium hydroxide / water / 0 - 20 °C
6.1: Jone's reagent / acetone / 0 - 20 °C
7.1: chlorosulfonic acid / dichloromethane / 0.75 h / 20 °C
View Scheme
参考文献
Roesner, Stefan; Casatejada, Javier Mansilla; Elford, Tim G.; Sonawane, Ravindra P.; Aggarwal, Varinder K.
Organic Letters, 2011 , vol. 13, # 21 p. 5740 - 5743
