2Br(1-)*C46H48N4O2(2+); palladium diacetate; sodium carbonate in N,N-dimethyl acetamide T=140°C; Heck reaction; 10 h; Inert atmosphere; stereoselective reaction;

tetraethylammonium bromide; sodium acetate; palladium in N,N-dimethyl acetamide T=135 - 140°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

tributyl-amine in N,N-dimethyl-formamide T=120°C; Heck-Mizoroki reaction;

1: 1.) aq. hydrobromic acid, sodium nitrite, 2.) cuprous chloride / acetone / 3.08 h / 3 - 5 °C 2: triethylamine / ethanol / 3 h / Heating View Scheme

1: tetrakis(triphenylphosphine) palladium(0); trimethylsilylazide / 1,2-dichloro-ethane / 1 h / Inert atmosphere; Reflux 2: sulfur; 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,2-dichloro-ethane / 1 h / Inert atmosphere; Reflux View Scheme