1: 60 percent / 2.2 M NaOH, 30percent H2O2 / H2O; acetone / 1.) 40 deg C, 60 min; 2.) 50 deg C, 90 min 2: 1.) n-butyllithium / 1.) THF, ethyl ether, hexane, -95 deg C, 60 min; 2.) THF, ethyl ether, hexane, (-95 deg C) - room temperature 3: i-Bu2AlH / hexane View Scheme

[Rh(OH)((S)-binap)]2 in tetrahydrofuran T=40°C; 12 h;