1.1: hydrogenchloride / ethanol; water / Inert atmosphere 2.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 5 - 10 °C / Inert atmosphere; Large scale reaction 3.1: acetonitrile / 2 h / Reflux; Inert atmosphere; Large scale reaction 4.1: ethanol; acetyl chloride / 2 h / 45 °C / Inert atmosphere; Large scale reaction 5.1: triethylamine / dichloromethane / -10 °C / Inert atmosphere; Large scale reaction 6.1: methanesulfonic acid; water / 10 h / 70 °C / Inert atmosphere; Large scale reaction 6.2: Inert atmosphere; Large scale reaction View Scheme