4-氯-7-甲氧基喹啉-3-羧酸乙酯合成路线 （共 7 条）
反应条件
trichlorophosphate in 1,4-dioxane T=120°C; 1 h;
参考文献
Zhang, Yiqun; Guiguemde, W. Armand; Sigal, Martina; Zhu, Fangyi; Connelly, Michele C.; Nwaka, Solomon; Guy, R. Kiplin
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 7 p. 2756 - 2766
反应条件
trichlorophosphate 5 h; Heating;
参考文献
Karolak-Wojciechowska, Janina; Lange, Jerzy; Ksiazek, Waldemar; Gniewosz, Malgorzata; Rump, Slawomir
Farmaco, 1998 , vol. 53, # 8-9 p. 579 - 585
反应条件
1: 79 percent / 2 h / 110 - 115 °C 2: various solvent(s) / 0.5 h / 250 °C 3: 67 percent / POCl3 / 5 h / Heating View Scheme
参考文献
Farmaco, , vol. 53, # 8-9 p. 579 - 585
反应条件
1: 79 percent / 2 h / 110 - 115 °C 2: various solvent(s) / 0.5 h / 250 °C 3: 67 percent / POCl3 / 5 h / Heating View Scheme
参考文献
Farmaco, , vol. 53, # 8-9 p. 579 - 585
反应条件
1: various solvent(s) / 0.5 h / 250 °C 2: 67 percent / POCl3 / 5 h / Heating View Scheme
参考文献
Farmaco, , vol. 53, # 8-9 p. 579 - 585
反应条件
hydrogen; sodium hydrogencarbonate; palladium 10 on activated carbon in acetic acid
参考文献
MERCK and CO., INC.
Patent: WO2006/14618 A2, 2006 ;
Location in patent: Page/Page column 38 ;
WO 2006/014618 A2
反应条件
sodium hydroxide; ethanol
T=20°C; 72 h;
参考文献
MERCK SHARP and DOHME LIMITED
Patent: WO2005/47279 A1, 2005 ;
Location in patent: Page/Page column 54 ;
WO 2005/047279 A1
