2,3-二氢-1H-吡咯并[1,2-A]苯并咪唑合成路线 （共 35 条）
反应条件
hydrogen; dirhodium tetraacetate; triphenylphosphine
T=70°C; P=20685.9 Torr;
参考文献
Anastasiou; Chaouk; Jackson
Tetrahedron Letters, 1991 , vol. 32, # 22 p. 2499 - 2500
反应条件
1.1: trichlorophosphate / toluene / 2 h / 0 °C
1.2: 4 h / Reflux
1.3: pH 10
2.1: copper(l) iodide; potassium carbonate; N-methyl-2-(methylamino)ethylamine / acetonitrile / 1 h / 80 °C / Inert atmosphere
View Scheme
参考文献
Liubchak, Kostiantyn; Nazarenko, Kostiantyn; Tolmachev, Andrey
Tetrahedron, 2012 , vol. 68, # 14 p. 2993 - 3000
反应条件
iron; acetic acid
0.5 h; Reflux;
参考文献
Alonso, Jorge; Halland, Nis; Nazare, Marc; R'Kyek, Omar; Urmann, Matthias; Lindenschmidt, Andreas
European Journal of Organic Chemistry, 2011 , # 2 p. 234 - 237
参考文献
Reppe et al.
Justus Liebigs Annalen der Chemie, 1955 , vol. 596, p. 1,175, 209
反应条件
1: With diisobutylaluminium hydride in toluene
T=0°C; 23 h; Inert atmosphereReflux;
2: With water; NAF in toluene; benzene
T=0 - 20°C; 0.333333 h; Inert atmosphere; regioselective reaction;
参考文献
Shvidenko, Tatyana; Nazarenko, Kostiantyn; Shvidenko, Konstantin; Kostyuk, Aleksandr
Tetrahedron Letters, 2014 , vol. 55, # 1 p. 279 - 281
