5-甲基-6H-吡啶并[3,4-h]咔唑-9-醇合成路线 （共 13 条）
反应条件
1: 40 percent / 10 percent palladium/carbon / dioxane; decahydronaphthalene / 1 h / 180 - 185 °C
2: 71 percent / hydrogen chloride / methanol; pyridine / 0.67 h / 190 °C
View Scheme
参考文献
Gouyette; Reynaud; Sadet; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 6 p. 503 - 510
反应条件
1: 60 percent / 6 N hydrochloric acid / 7.5 h / Heating
2: 27 percent / 10 percent palladium/charcoal / various solvent(s) / 50 h / Heating
3: 71 percent / hydrogen chloride / methanol; pyridine / 0.67 h / 190 °C
View Scheme
参考文献
Gouyette; Reynaud; Sadet; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 6 p. 503 - 510
反应条件
1: 22.4 percent / 10 percent palladium/carbon / decahydronaphthalene / 6 h / 205 °C
2: 71 percent / hydrogen chloride / methanol; pyridine / 0.67 h / 190 °C
View Scheme
参考文献
Gouyette; Reynaud; Sadet; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 6 p. 503 - 510
