(R)-氮杂环丁烷-2-羧酸合成路线 (共 4 条)
反应条件
hydrogen; palladium on activated charcoal in methanol 96 h;
参考文献
Couty, Francois; Evano, Gwilherm; Vargas-Sanchez, Monica; Bouzas, Gloria
Journal of Organic Chemistry, 2005 , vol. 70, # 22 p. 9028 - 9031
反应条件
hydrogen; palladium on activated charcoal in methanol 72 h;
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 4 p. 407 - 412
反应条件
hydrogenchloride; HNO2 T=60°C; Erhitzen des Reaktionsprodukts mit wss. Ba(OH)2;
参考文献
Biochemical Journal, , vol. 64, p. 323,330
反应条件
in 1,4-dioxane; water T=0 - 20°C; 1 h;
参考文献
CYTOKINETICS, INCORPORATED
Patent: WO2008/16643 A2, 2008 ;
Location in patent: Page/Page column 257 ;