1-BOC-4-氰甲基哌嗪合成路线 （共 3 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C; 12 h;
参考文献
MERCK SHARP and DOHME CORP.; MORRIELLO, Gregori, J.; WENDT, Harvey, R.; EDMONDSON, Scott, D.
Patent: WO2012/12314 A1, 2012 ;
Location in patent: Page/Page column 58 ;
WO 2012/012314 A1
反应条件
triethylamine in tetrahydrofuran
T=20°C;
参考文献
Bristol-Myers Squibb Company
Patent: US2007/249579 A1, 2007 ;
Location in patent: Page/Page column 132 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
AstraZeneca AB
Patent: US2004/48881 A1, 2004 ;
US 20040048881 A1
