4-氨基-2,5-二氟苯甲酸合成路线 （共 3 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol P=3000.3 Torr;
参考文献
US2007/270401 A1, ;
Page/Page column 6 ;
反应条件
1: With sulfuric acid; water in 1,4-dioxane T=80°C; 96 h; 2: With sodium hydroxide in 1,4-dioxane; water 3: With hydrogenchloride in water Product distribution / selectivity;
参考文献
WO2011/141180 A1, ;
Page/Page column 77 ;
WO 2011/141180 A1
反应条件
1: With thionyl chloride
T=0 - 50°C; 3.66667 h;
2: With sodium hydrogencarbonate in water; ethyl acetate
参考文献
STEURER, Steffen; BETZEMEIER, Bodo; MCCONNELL, Darryl; GERSTBERGER, Thomas; GRAUERT, Matthias; HOFFMANN, Matthias; IMPAGNATIELLO, Maria; van der VEEN, Lars; WEYER-CZERNILOFSKY, Ulrike
Patent: US2007/270401 A1, 2007 ;
Location in patent: Page/Page column 6 ;
