乙基7-甲基-1H-吲哚-3-羧酸酯合成路线 (共 1 条)
反应条件
1: 7-methyl-indole; 2,2,2-trichloroacetyl chloride With pyridine in tetrahydrofuran
T=0 - 20°C; 17 h; Inert atmosphere;
2: ethanol With potassium hydroxide in water
T=20°C; 6 h; Reflux;
参考文献
Cao, Trung; Deitch, Joshua; Linton, Elizabeth C.; Kozlowski, Marisa C.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 10 p. 2448 - 2451