sodium hydroxide in methanol; water T=50°C; 6 h;

Pd2(PPh3)2Cl2; sodium carbonate in tetrahydrofuran; water T=60°C; Inert atmosphere;

1: sodium hydroxide / water; methanol / 6 h / 50 °C 2: palladium diacetate; N-acetyl-glycine; potassium acetate; [bis(acetoxy)iodo]benzene / tert-butyl alcohol / 12 h / 80 °C / |Sealed tube View Scheme