2-氨基甲酰基-3-硝基苯甲酸合成路线 （共 22 条）
反应条件
1: aq. KOH; Br2 / 80 °C 2: NaOH; hydrazine hydrate; Raney Ni 3: K3Fe(CN)6 / methanol / Heating View Scheme
参考文献
Xue, Fei; Luo, Xianjin; Ye, Chenghao; Ye, Weidong; Wang, Yue
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 8 p. 2641 - 2649
反应条件
1: 93 percent / Br2; aq. KOH / 3 h / 60 °C
2: 66 percent / H2 / 10percent Pd/C / methanol / 760.05 Torr
3: 20 percent / PPA / 1 h / 150 - 160 °C
4: SOCl2 / tetrahydrofuran; dimethylformamide / 20 °C
5: conc. aq. NH3 / tetrahydrofuran; dimethylformamide
View Scheme
参考文献
White; Almassy; Calvert; Curtin; Griffin; Hostomsky; Maegley; Newell; Srinivasan; Golding
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4084 - 4097
