1.1: 15.2 g / 1,1,2-trichloro-1,2,2-trifluoroethane; BuLi / tetrahydrofuran; hexane / -75 °C 2.1: N,N-dimethylethanolamine; BuLi / hexane / 0.75 h / -75 °C 2.2: 62 percent / diethyl ether; hexane 3.1: 84 percent / tetrabutylammonium fluoride trihydrate / diethyl ether / 20 h / 25 °C View Scheme

1.1: 15.2 g / 1,1,2-trichloro-1,2,2-trifluoroethane; BuLi / tetrahydrofuran; hexane / -75 °C 2.1: N,N-dimethylethanolamine; BuLi / hexane / 0.75 h / -75 °C 2.2: 62 percent / diethyl ether; hexane 3.1: 84 percent / tetrabutylammonium fluoride trihydrate / diethyl ether / 20 h / 25 °C 4.1: 67 percent / ammonium formate / Pd/C / methanol / 6 h / 50 °C View Scheme