n-butyllithium; iodine; diisopropylamine 1.) THF, hexane, -78 grad C, 30 min, 2.) THF, hexane, -78 grad C, then slowly allowed to warm to room temperature overnight.; Yield given. Multistep reaction;
参考文献
Gribble, Gordon W.,; Saulnier, Mark G.
Tetrahedron Letters, 1980 , vol. 21, p. 4137 - 4140
caesium carbonate; tris-(dibenzylideneacetone)dipalladium(0); tri-cyclo-hexyl-phosphine in 1,4-dioxane
T=95°C; 18 h;
参考文献
MERCK and CO., INC.; ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.
Patent: WO2008/57209 A1, 2008 ;
Location in patent: Page/Page column 55 ;
WO 2008/057209 A1
