反应条件
1.1: 70 percent / (i-Pr)2NH / PdCl2(PPh3)2; CuI / tetrahydrofuran
2.1: aq. KOH / methanol / 12 h
3.1: 1.50 g / [2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium]*BF4; (i-Pr)2NEt / CH2Cl2 / 12 h
4.1: BuLi / hexane; tetrahydrofuran / 0.25 h / -78 °C
4.2: 79 percent / hexane; tetrahydrofuran / -78 - 20 °C
View Scheme
参考文献
Wessig, Pablo; Mueller, Gunnar; Herre, Robert; Kuehn, Andreas
Helvetica Chimica Acta, 2006 , vol. 89, # 11 p. 2694 - 2719
