4,4'-(1,5-戊烷二基)二氧基二苯甲醛合成路线 （共 3 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=100°C; 12 h;
参考文献
Kueny-Stotz, Marie; Brouillard, Raymond; Chassaing, Stefan
Synlett, 2012 , vol. 23, # 14 p. 2053 - 2058,6
Title/Abstract Show Details
Kueny-Stotz, Marie; Brouillard, Raymond; Chassaing, Stefan
Synlett, 2012 , vol. 23, # 14 p. 2053 - 2058
反应条件
sodium ethanolate
1.) ethanol, reflux, 4 h, 2.) reflux, 48 h; Yield given. Multistep reaction;
参考文献
Nesunts, N. S.; Avetisyan, S. A.; Dzhagatspanyan, I. A.; Akopyan, N. E.; Mndzhoyan, O. L.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 7 p. 480 - 484
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 7 p. 801 - 806
反应条件
1: 85.2 percent / piperidine, glacial acetic acid / benzene / Heating
2: 2.) NaOH / 1.) water, ethanol, heating, 2 h, 2.) ethylene glycol, heating, 40 h
3: 1.) acetic anhydride, 2.) ammonia / 1.) heating, 6 h, 2.) ethyl acetate, 2 h
4: 1 h / 200 - 220 °C
View Scheme
参考文献
Nesunts, N. S.; Avetisyan, S. A.; Dzhagatspanyan, I. A.; Akopyan, N. E.; Mndzhoyan, O. L.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 7 p. 480 - 484
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 7 p. 801 - 806
