4-氯-2-丁炔基氨基甲酸叔丁酯合成路线 （共 4 条）
反应条件
sodium hydroxide in 1,4-dioxane; water
2 h; Ambient temperature;
参考文献
Sasaki, Andre N.; Bricas, Evanghelos
Tetrahedron Letters, 1980 , vol. 21, p. 4263 - 4264
反应条件
1: 1-Amino-4-chloro-2-butyne hydrochloride With sodium hydroxide in 1,4-dioxane; water
0.5 h;
2: carbonic acid di-tert-butyl ester in trans-1,3-dioxane; water
T=20 - 25°C; 8 h;
参考文献
G. D. Searle and Co.
Patent: US6344483 B1, 2002 ;
Location in patent: Page column 19 ;
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran; water
参考文献
Bridger, Gary; Kaller, Al; Harwig, Curtis; Skerlj, Renato; Bogucki, David; Wilson, Trevor R.; Crawford, Jason; McEachern, Ernest J.; Atsma, Bem; Nan, Siqiao; Zhou, Yuanxi; Schols, Dominique; Smith, Christopher D.; Di Fluri, Maria R.
Patent: US2004/19058 A1, 2004 ;
US 20040019058 A1
参考文献
Nassal; Buc; Wieland
1983 , vol. NO. 9, p. 1524 - 1532
