4-[(E)-2-(2-吡啶基)乙烯基]苯酚合成路线 （共 9 条）
反应条件
acetic anhydride
und Erhitzen mit Wasser auf 140grad;
参考文献
Saxena et al.
Journal of the Chemical Society, 1959 , p. 1579,1585
反应条件
boron tribromide in dichloromethane
T=-10 - 0°C;
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
2: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: 94.4 percent / LiAlH4 / diethyl ether / 4 h / Heating
2: 93.8 percent / SOCl2 / diethyl ether / 3 h / 20 °C
3: 4 h / Heating
4: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
5: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: 4 h / Heating
2: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
3: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: 93.8 percent / SOCl2 / diethyl ether / 3 h / 20 °C
2: 4 h / Heating
3: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
4: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: 95.3 percent / K2CO3 / acetone / 3 h / Heating
2: 94.4 percent / LiAlH4 / diethyl ether / 4 h / Heating
3: 93.8 percent / SOCl2 / diethyl ether / 3 h / 20 °C
4: 4 h / Heating
5: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
6: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
ethanol
isomer(ic) II;
参考文献
Chiang; Hartung
Journal of Organic Chemistry, 1945 , vol. 10, p. 26
反应条件
sodium hydroxide; sodium amalgam; water
参考文献
Papa et al.
Journal of the American Chemical Society, 1951 , vol. 73, p. 253
