773837-37-9合成路线 （共 596 条）
反应条件
sulfuric acid; acetic acid in water T=45°C; Ritter reaction; 0.05 h;
参考文献
Brandt, Johan C.; Elmore, Simon C.; Robinson, Richard I.; Wirth, Thomas
Synlett, 2010 , # 20 art. no. D26910ST, p. 3099 - 3103
反应条件
tetrabutylammomium bromide in water T=20°C; 1.83333 h;
参考文献
Chinese Chemical Letters, , vol. 22, # 3 p. 300 - 302
反应条件
CuO in N,N-dimethyl-formamide T=100°C;
参考文献
Yapuri, Umanadh; Palle, Sadanandam; Gudaparthi, Omprakash; Narahari, Srinivasa Reddy; Rawat, Dhwajbahadur K.; Mukkanti, Khagga; Vantikommu, Jyothi
Tetrahedron Letters, 2013 , vol. 54, # 35 p. 4732 - 4734
反应条件
copper (I) cyanide in N,N-dimethyl-formamide T=150°C; 5 h;
参考文献
LegoChem Biosciences, Inc.; CHO, Young Lag; BAEK, Sung Yoon; CHAE, Sang Eun; KIM, Sun Young; LEE, Hong Bum; LEE, Hyang Sook; OH, Kyuman; HEO, Hye Jin; PARK, Tae Kyo; WOO, Sung Ho; KIM, Yong Zu
Patent: EP2692727 A2, 2014 ;
Location in patent: Paragraph 0149-0150 ;
反应条件
potassium acetate in water byproducts: KCN;
参考文献
Doklady Akademii Nauk SSSR, , vol. 81, p. 585 - 588
C. A., , p. 3386
反应条件
copper (I) cyanide in 1-methyl-pyrrolidin-2-one
参考文献
Chen, Jyh-Chien; Chiang, Chi-Jui; Chiu, Jen-Chun; Ju, Jyh-Jong
Chemical Communications, 2012 , vol. 48, # 62 p. 7756 - 7758
反应条件
1: 4-methoxy-benzaldehyde With (1R,2R)-cyclohexane-1,2-diylbis(2-azaethenyl-3-tert-butyl-2-hydroxybenzo-5-sulfonic acid) disodium salt; Manganese (II) acetate in methanol T=20°C; 0.5 h; 2: sodium cyanide in methanol T=20°C; 24 h; optical yield given as percent eeenantioselective reaction;
参考文献
Qu, Yanyang; Jing, Linhai; Wu, Zhiqing; Wu, Di; Zhou, Xiangge
Tetrahedron Asymmetry, 2010 , vol. 21, # 2 p. 187 - 190
反应条件
1: methyl-4-chloroacetoacetate With isopropyl alcohol T=30°C; pH=7.5; 4 h; aq. bufferEnzymatic reaction; 2: sodium cyanide With halohydrin dehalogenase from Agrobacterium radiobacter AD1 T=30°C; pH=7.5; 44 h; aq. bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 14 p. 2293 - 2298
