773837-37-9合成路线 （共 596 条）
反应条件
ruthenium trichloride; oxygen; acetic acid in methanol T=60°C; P=760.051 Torr; 2 h;
参考文献
Murahashi, Shun-Ichi; Nakae, Takahiro; Terai, Hiroyuki; Komiya, Naruyoshi
Journal of the American Chemical Society, 2008 , vol. 130, # 33 p. 11005 - 11012
反应条件
1: benzaldehyde With (1R,2R)-cyclohexane-1,2-diylbis(2-azaethenyl-3-tert-butyl-2-hydroxybenzo-5-sulfonic acid) disodium salt; Manganese (II) acetate in methanol T=20°C; 0.5 h; 2: sodium cyanide in methanol T=20°C; 24 h; optical yield given as percent eeenantioselective reaction;
参考文献
Qu, Yanyang; Jing, Linhai; Wu, Zhiqing; Wu, Di; Zhou, Xiangge
Tetrahedron Asymmetry, 2010 , vol. 21, # 2 p. 187 - 190
反应条件
Prunus armeniaca from Himalayan plum in water; dimethyl sulfoxide pH=4; 0.0833333 h; citrate bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
Zheng, Zubiao; Zi, Yan; Li, Zhongzhou; Zou, Xinzhuo
Tetrahedron Asymmetry, 2013 , vol. 24, # 8 p. 434 - 439
反应条件
in ethanol; water T=100°C; 8.5 h;
参考文献
Daiichi Sankyo Company, Limited; MORI, Makoto; FUJII, Kunihiko; INUI, Masaharu; BABA, Takayuki; ONISHI, Yukari; AOYAGI, Atsushi
Patent: EP2700643 A1, 2014 ;
Location in patent: Paragraph 0188 ;
反应条件
in N,N-dimethyl-formamide T=20 - 25°C; 18 h; Inert atmosphere;
参考文献
PFIZER INC.; BROWN, Matthew Frank; MARFAT, Anthony; MELNICK, Michael Joseph; REILLY, Usa
Patent: WO2011/45703 A2, 2011 ;
Location in patent: Page/Page column 44 ;
WO 2011/045703 A2
反应条件
water in ethanol 72 h; Reflux;
参考文献
GLAXOSMITHKLINE LLC; GHERGUROVICH, Jonathan, Michael; MOORE, Michael, Lee; PARRISH, Cynthia, Ann; RIDGERS, Lance, Howard; YU, Hongyi
Patent: WO2013/28447 A1, 2013 ;
Location in patent: Page/Page column 93 ;
反应条件
1: in water T=25°C; 8 h; 2: With sulfuric acid in water
参考文献
Letters in Organic Chemistry, , vol. 9, # 7 p. 520 - 521
反应条件
in ethanol; water 4 h; Reflux;
参考文献
Radulovic, Niko S.; Dekic, Milan S.; Stojanovic-Radic, Zorica Z.
Phytochemistry Letters, 2012 , vol. 5, # 2 p. 351 - 357
反应条件
in acetonitrile Reflux;
参考文献
European Journal of Medicinal Chemistry, , vol. 45, # 1 p. 11 - 18
反应条件
in 1,4-dioxane; water T=0 - 20°C; 16 h;
参考文献
APPLIED RESEARCH SYSTEMS ARS HOLDING N. V.
Patent: WO2004/98607 A1, 2004 ;
Location in patent: Page/Page column 43-44 ;
WO 2004/098607 A1
