773837-37-9合成路线 （共 596 条）
反应条件
tetrabutylammomium bromide in water; acetonitrile T=55°C; 2 h; Product distribution / selectivity;
参考文献
Lonza Ltd
Patent: EP2455365 A1, 2012 ;
Location in patent: Page/Page column 6 ;
反应条件
in acetonitrile 4 h; Reflux;
参考文献
Liu, Tao; Dong, Xiaowu; Xue, Na; Wu, Rui; He, Qiaojun; Yang, Bo; Hu, Yongzhou
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 17 p. 6279 - 6285
反应条件
tri-tert-butyl phosphine; Pd2(dba)5; zinc in tetrahydrofuran; acetonitrile T=70°C; 2 h;
参考文献
Ushkov, Alexander V.; Grushin, Vladimir V.
Journal of the American Chemical Society, 2011 , vol. 133, # 28 p. 10999 - 11005
反应条件
sodium hydroxide in water-d2 a mixt. of NaCN, NaOH and D2O was refluxed for 2 wk; distd., the residue was dissolved in H2O, HCl to pH 8.0 was added;
参考文献
Wong; Whitesides
Journal of the American Chemical Society, 1983 , vol. 105, # 15 p. 5012 - 5014
反应条件
CuO in N,N-dimethyl-formamide T=100°C;
参考文献
Tetrahedron Letters, , vol. 54, # 35 p. 4732 - 4734
反应条件
sulfuric acid; sodium hydroxide in water T=40°C; pH=7.3; Enzymatic reaction;
参考文献
Ma, Steven K.; Gruber, John; Davis, Chris; Newman, Lisa; Gray, David; Wang, Alica; Grate, John; Huisman, Gjalt W.; Sheldon, Roger A.
Green Chemistry, 2010 , vol. 12, # 1 p. 81 - 86
反应条件
vector pACYCDuet-RB and vector pET30-halohydrin dehalogenase in Escherichia coli BL21 (DE3) in aq. buffer T=30°C; pH=7; 2 h; Enzymatic reaction; stereoselective reaction;
参考文献
Chen, Shao-Yun; Yang, Chen-Xi; Wu, Jian-Ping; Xu, Gang; Yang, Li-Rong
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 16 p. 3179 - 3190
反应条件
vector pCDFDuet-HF and vector pET30-(S)-alcohol dehydrogenase in Escherichia coli BL21(DE3) in aq. buffer T=30°C; pH=7; 10 h; Enzymatic reaction; stereoselective reaction;
参考文献
Chen, Shao-Yun; Yang, Chen-Xi; Wu, Jian-Ping; Xu, Gang; Yang, Li-Rong
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 16 p. 3179 - 3190
参考文献
Lim, Jung Yun; Jeon, Nan Young; Park, A-Reum; Min, Bora; Kim, Bum Tae; Park, Seongsoon; Lee, Hyuk
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 9 p. 1808 - 1816
反应条件
ammonia; nickel dichloride in aq. phosphate buffer; water T=30°C; pH=8; Enzymatic reaction; Kinetics;
参考文献
Schallmey, Marcus; Floor, Robert J.; Hauer, Bernhard; Breuer, Michael; Jekel, Peter A.; Wijma, Hein J.; Dijkstra, Bauke W.; Janssen, Dick B.
ChemBioChem, 2013 , vol. 14, # 7 p. 870 - 881
