1,2-二(4-叔丁基苯基)-2-羟基乙烷酮合成路线 （共 5 条）
反应条件
samarium; potassium iodide; copper(l) chloride in tetrahydrofuran
T=20°C; 2 h; Inert atmosphere;
参考文献
Liu, Yongjun; Wang, Hui; Fu, Yulong; Qi, Yan; Yang, Kuiwei
Synthetic Communications, 2014 , vol. 44, # 2 p. 259 - 266
反应条件
hydrogenchloride; Zn–Hg amalgam in ethanol
1.) 0-5 deg C, 6 h, 2.) r.t., overnight; Yield given;
参考文献
Han, G. Y.; Han, P. F.; Perkins, J.; McBay, H. C.
Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4695 - 4700
反应条件
oxygen; potassium carbonate in water
T=100°C; 0.833333 h; Air atmosphere; chemoselective reaction;
参考文献
Sodhi, Ravinderpal Kour; Paul, Satya
Catalysis Letters, 2011 , vol. 141, # 4 p. 608 - 615
反应条件
1: zinc amalgam, conc. HCl / aq. ethanol / 1.) 0-5 deg C, 6 h, 2.) r.t., overnight
2: bromine / Ambient temperature; Irradiation
3: N,N-dimethylaniline / 24 h / Heating; or KOH in dioxane, reflux, 4 h
4: bromine / CCl4 / dark, cold conditions
View Scheme
参考文献
Han, G. Y.; Han, P. F.; Perkins, J.; McBay, H. C.
Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4695 - 4700
反应条件
1: zinc amalgam, conc. HCl / aq. ethanol / 1.) 0-5 deg C, 6 h, 2.) r.t., overnight
2: bromine / Ambient temperature; Irradiation
3: N,N-dimethylaniline / 24 h / Heating; or KOH in dioxane, reflux, 4 h
4: bromine / CCl4 / dark, cold conditions
5: N,N-dimethylaniline / 24 h / Heating; or KOH in dioxane, reflux
View Scheme
参考文献
Han, G. Y.; Han, P. F.; Perkins, J.; McBay, H. C.
Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4695 - 4700
