4-(羟基甲基)苯基丙酸酯合成路线 (共 3 条)
反应条件
sodium tetrahydroborate in tetrahydrofuran
T=0 - 20°C; 1 h; Inert atmosphere;
参考文献
Zakhari, Joseph S.; Kinoyama, Isao; Hixon, Mark S.; Di Mola, Antonia; Globisch, Daniel; Janda, Kim D.
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 21 p. 6203 - 6209
反应条件
triethylamine in dichloromethane
T=20°C;
参考文献
Clendennen, Stephanie Kay; Boaz, Neil Warren; Clauson, Jeffrey M.
Patent: US2008/306144 A1, 2008 ;
Location in patent: Page/Page column 8 ;
反应条件
1: triethylamine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
2: sodium tetrahydroborate / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere
View Scheme
参考文献
Zakhari, Joseph S.; Kinoyama, Isao; Hixon, Mark S.; Di Mola, Antonia; Globisch, Daniel; Janda, Kim D.
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 21 p. 6203 - 6209