2-氨基-5-(4-氟苯基)噻唑合成路线 （共 3 条）
反应条件
hydrogenchloride in 1,4-dioxane; water 6 h; Reflux;
参考文献
Asinex Limited; KAZULKIN, Denis Nikolaevich; KOCHUBEY, Valeriy Sergeevich
Patent: EP2719696 A1, 2014 ;
Location in patent: Paragraph 0206-0209 ;
反应条件
1: potassium phosphate; palladium diacetate; tri-cyclo-hexyl-phosphine / N,N-dimethyl-formamide / 1 h / 140 °C / |Microwave irradiation; |Inert atmosphere 2: hydrogenchloride / water; 1,4-dioxane / 6 h / |Reflux View Scheme
反应条件
potassium hydroxide in methanol
参考文献
Zhurnal Organicheskoi Khimii, , vol. 15, p. 2351 - 2356,2129 - 2133
