1,3-二氯异喹啉合成路线

Perner, Richard J.; DiDomenico, Stanley; Koenig, John R.; Gomtsyan, Arthur; Bayburt, Erol K.; Schmidt, Robert G.; Drizin, Irene; Guo, Zhu Zheng; Turner, Sean C.; Jinkerson, Tammie; Brown, Brian S.; Keddy, Ryan G.; Lukin, Kurill; McDonald, Heath A.; Honore, Prisca; Mikusa, Joe; Marsh, Kennan C.; Wetter, Jill M.; St. George, Karen; Jarvis, Michael F.; Faltynek, Connie R.; Lee, Chih-Hung
Journal of Medicinal Chemistry, 2007 , vol. 50, # 15 p. 3651 - 3660

7742-73-61,3-二氯异喹啉

10296-47-63-氯-5-硝基异喹啉

参考文献

Perner, Richard J.; DiDomenico, Stanley; Koenig, John R.; Gomtsyan, Arthur; Bayburt, Erol K.; Schmidt, Robert G.; Drizin, Irene; Guo, Zhu Zheng; Turner, Sean C.; Jinkerson, Tammie; Brown, Brian S.; Keddy, Ryan G.; Lukin, Kurill; McDonald, Heath A.; Honore, Prisca; Mikusa, Joe; Marsh, Kennan C.; Wetter, Jill M.; St. George, Karen; Jarvis, Michael F.; Faltynek, Connie R.; Lee, Chih-Hung
Journal of Medicinal Chemistry, 2007 , vol. 50, # 15 p. 3651 - 3660

7742-73-61,3-二氯异喹啉

126653-00-71-哌嗪-1-异喹啉

参考文献

Matsuno, Kenji; Ushiki, Junko; Seishi, Takashi; Ichimura, Michio; Giese, Neill A.; Yu, Jin-Chen; Takahashi, Shusuke; Oda, Shoji; Nomoto, Yuji
Journal of Medicinal Chemistry, 2003 , vol. 46, # 23 p. 4910 - 4925

67-56-1甲醇+

7742-73-61,3-二氯异喹啉

24649-22-73-氯-1-甲氧基异喹啉

参考文献

AMBIT BIOSCIENCES CORPORATION; FARAONI, Raffaella; HADD, Michael, J.; HOLLADAY, Mark, W.; ROWBOTTOM, Martin; SETTI, Eduardo
Patent: WO2012/30944 A2, 2012 ;
Location in patent: Page/Page column 90 ;
WO 2012/030944 A2

7742-73-61,3-二氯异喹啉+

124-41-4甲醇钠

24649-22-73-氯-1-甲氧基异喹啉

参考文献

Gabriel
Chemische Berichte, 1886 , vol. 19, p. 2355,2363
Chemische Berichte, 1887 , vol. 20, p. 1198

7742-73-61,3-二氯异喹啉

19493-45-93-氯异喹啉

参考文献

ABBOTT LABORATORIES; GOMTSYAN, Arthur R.; VOIGHT, Eric A.; BAYBURT, Erol K.; CHEN, Jun; DAANEN, Jerome F.; DIDOMENICO, Stanley, Jr.; KORT, Michael E.; KYM, Philip R.; MCDONALD, Heath A.; PERNER, Richard J.; SCHMIDT, Robert G.
Patent: WO2010/45402 A1, 2010 ;
Location in patent: Page/Page column 87 ;
WO 2010/045402 A1