1: 87 percent / acetophenone / benzene / 12 h / Ambient temperature; Irradiation 2: 98 percent / 6 N HCl / H2O / 15 h / Heating View Scheme

1: 87 percent / acetophenone / benzene / 12 h / Ambient temperature; Irradiation 2: 98 percent / 6 N HCl / H2O / 15 h / Heating 3: NaOH / H2O; 2-methyl-propan-2-ol / 24 h / Ambient temperature View Scheme

1: 87 percent / acetophenone / benzene / 12 h / Ambient temperature; Irradiation 2: 98 percent / 6 N HCl / H2O / 15 h / Heating 3: NaOH / H2O; 2-methyl-propan-2-ol / 24 h / Ambient temperature 4: CH2Cl2 5: 66 percent / sodium m-periodate, ruthenium dioxide / acetonitrile; H2O; CCl4 / 504 h 6: thionyl chloride, HCl gas / CH2Cl2 / 1 h 7: 80 percent / Et3N / CH2Cl2 View Scheme

potassium tert-butylate in tetrahydrofuran T=-78 - 25°C;

sodium hydride in N,N-dimethyl-formamide; mineral oil T=23°C; 0.5 h;

in acetophenone; acetonitrile T=100°C; 2.5 h; Irradiation;