反应条件
1.1: Red-Al; sodium bis(2-methoxyethoxy)aluminum hydride / toluene; tetrahydrofuran / -10 - 0 °C
2.1: pyridine / CH2Cl2 / -5 - 0 °C
3.1: nitric acid; trifluoroacetic acid; trifluoroacetic anhydride / CH2Cl2 / -35 - -30 °C
4.1: NaOH; methanol / 23 °C
5.1: acetic acid; perchloric acid; hydrogen / Pd/C / 15.5 h / 2172.08 - 2585.81 Torr
5.2: NaHCO3 / H2O; CH2Cl2 / 23 °C / pH 8.0
View Scheme
参考文献
Waykole, Liladhar M.; McKenna, Joseph J.; Bach, Andrew; Prashad, Mahavir; Repic, Oljan; Blacklock, Thomas J.
Synthetic Communications, 2007 , vol. 37, # 9 p. 1445 - 1454
