3-(2-氯乙基)-1-[2-[2-(2-氯乙基氨基甲酰-亚硝基氨基)乙基二硫基]乙基]-1-亚硝基脲合成路线 （共 5 条）
反应条件
1: pyridine; toluene / Ambient temperature
2: 60 percent / ClNO / pyridine; CH2Cl2 / 3 h / -10 °C
3: dimethylformamide / 0.5 h / Ambient temperature
View Scheme
参考文献
Oiry; Pompon; Madelmont; Imbach
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 4 p. 311 - 314
反应条件
1: formic acid / Ambient temperature
2: NaNO2 / formic acid / 1 h / 10 °C
View Scheme
参考文献
Oiry; Pompon; Madelmont; Imbach
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 4 p. 311 - 314
反应条件
1: 60 percent / ClNO / pyridine; CH2Cl2 / 3 h / -10 °C
2: dimethylformamide / 0.5 h / Ambient temperature
View Scheme
参考文献
Oiry; Pompon; Madelmont; Imbach
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 4 p. 311 - 314
反应条件
sodium nitrite in formic acid
T=0 - 5°C; 3 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Oiry; Imbach
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 4 p. 305 - 309
反应条件
in N,N-dimethyl-formamide
0.5 h; Ambient temperature; Yield given;
参考文献
Oiry; Pompon; Madelmont; Imbach
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 4 p. 311 - 314
