(5-溴-2-甲基苯基)硼酸合成路线 （共 4 条）
反应条件
hydrogenchloride in tetrahydrofuran; hexane
参考文献
Cell Therapeutics, Inc.
Patent: US2004/204386 A1, 2004 ;
反应条件
1: 6-butyl-2-(2,5-dibromophenyl)-1,3,6,2-dioxazaborocane With n-butyllithium in tetrahydrofuran
T=-80°C; Inert atmosphere;
2: methyl iodide Inert atmosphere;
3: With water
Acidic conditions;
参考文献
Durka, Krzysztof; Lulinski, Sergiusz; Smetek, Jaromir; Dabrowski, Marek; Serwatowski, Janusz; Wozniak, Krzysztof
European Journal of Organic Chemistry, 2013 , # 15 p. 3023 - 3032
反应条件
1: With isopropylmagnesium chloride in tetrahydrofuran
2: With boric acid trimethyl ester in tetrahydrofuran
参考文献
Gong, Baoqing; Hong, Feng; Kohm, Cory; Jenkins, Scott; Tulinsky, John; Bhatt, Rama; De Vries, Peter; Singer, Jack W.; Klein, Peter
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2303 - 2308
反应条件
1.1: NaIO4; H2SO4; Ac2O / acetic acid
2.1: i-PrMgCl / tetrahydrofuran
2.2: B(OMe)3 / tetrahydrofuran
View Scheme
参考文献
Gong, Baoqing; Hong, Feng; Kohm, Cory; Jenkins, Scott; Tulinsky, John; Bhatt, Rama; De Vries, Peter; Singer, Jack W.; Klein, Peter
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2303 - 2308
