N-(2,6-二甲基苯基)-5-羟基己酰胺合成路线 （共 5 条）
反应条件
sodium tetrahydroborate in diethyl ether; water
2 h;
参考文献
Tenthorey; Block; Ronfeld; McMaster; Byrnes
Journal of Medicinal Chemistry, 1981 , vol. 24, # 7 p. 798 - 806
反应条件
anhydrous diethylamine hydrochloride; sodium cyanoborohydride in acetonitrile
24 h; Heating;
参考文献
Tenthorey; Block; Ronfeld; McMaster; Byrnes
Journal of Medicinal Chemistry, 1981 , vol. 24, # 7 p. 798 - 806
反应条件
1: 40 percent / dicyclohexylcarbodiimide / CH2Cl2 / 5 - 25 °C
2: 49 percent / NaBH4 / diethyl ether; H2O / 2 h
View Scheme
参考文献
Tenthorey; Block; Ronfeld; McMaster; Byrnes
Journal of Medicinal Chemistry, 1981 , vol. 24, # 7 p. 798 - 806
反应条件
1: NaI / ethanol / 48 h / Heating
2: 40 percent / dicyclohexylcarbodiimide / CH2Cl2 / 5 - 25 °C
3: 49 percent / NaBH4 / diethyl ether; H2O / 2 h
View Scheme
参考文献
Tenthorey; Block; Ronfeld; McMaster; Byrnes
Journal of Medicinal Chemistry, 1981 , vol. 24, # 7 p. 798 - 806
反应条件
1: 40 percent / dicyclohexylcarbodiimide / CH2Cl2 / 5 - 25 °C
2: 49 percent / NaBH4 / diethyl ether; H2O / 2 h
View Scheme
参考文献
Tenthorey; Block; Ronfeld; McMaster; Byrnes
Journal of Medicinal Chemistry, 1981 , vol. 24, # 7 p. 798 - 806
