(R)-(+)-1,2-环氧辛烷合成路线 （共 27 条）
反应条件
titanium(IV) isopropylate; wqf-II-250; dihydrogen peroxide in dichloromethane; water; 1,2-dichloro-ethane T=20°C; 100 h; enantioselective reaction;
参考文献
Berkessel, Albrecht; Guenther, Thomas; Wang, Qifang; Neudoerfl, Joerg-M.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 32 p. 8467 - 8471
Angew. Chem., 2013 , vol. 125, # 32 p. 8625 - 8629
反应条件
C8F17COOH; water; (R,R)-Co(III)(salen) in toluene T=20°C; 15 h;
参考文献
Tetrahedron, , vol. 58, # 20 p. 3943 - 3949
反应条件
T=30°C; 70 h; Pseudomonas oleovorans, P1-medium;
参考文献
Smet, Marie-Jose de; Witholt, Bernard; Wynberg, Hans
Journal of Organic Chemistry, 1981 , vol. 46, # 15 p. 3128 - 3131
反应条件
water; Cr(III)-endo,endo-2,5-diaminonorbornane-salen in tetrahydrofuran T=20°C; 24 h;
参考文献
Berkessel, Albrecht; Ertuerk, Erkan
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 18 p. 2619 - 2625
反应条件
1: With lithium bromide in tetrahydrofuran 3 h; 2: in diethyl ether 12 h; 3: With potassium carbonate in methanol T=0°C; 3 h; Further stages.;
参考文献
Paddon-Jones; McErlean; Hayes; Moore; Konig; Kitching
Journal of Organic Chemistry, 2001 , vol. 66, # 22 p. 7487 - 7495
反应条件
sodium tetrahydroborate in ethanol; dichloromethane T=0°C; 0.25 h;
参考文献
Journal of the American Chemical Society, , vol. 126, # 13 p. 4108 - 4109
反应条件
Agrobacterium radiobacter AD1 halohydrin dehalogenase HheC; isopropyl alcohol T=30°C; 24 h; aq. bufferEnzymatic reaction; optical yield given as percent eestereoselective reaction;
参考文献
Schrittwieser, Joerg H.; Lavandera, Ivan; Seisser, Birgit; Mautner, Barbara; Lutje Spelberg, Jeffrey H.; Kroutil, Wolfgang
Tetrahedron Asymmetry, 2009 , vol. 20, # 4 p. 483 - 488
反应条件
isopropyl alcohol in various solvent(s) T=30°C; pH=7.5; 5 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 8-9 p. 1399 - 1404
反应条件
1.1: 40 percent / (AcO)(H2O)(S,S)N,N'bis(3,5-di-t-Bu-Sal-1,2-cC6H11diNH2)CoIII / H2O / 16 h 2.1: SOCl2; Et3N / CH2Cl2 / 0.08 h / 0 °C 3.1: 1.0 g / NaIO4 / RuCl3 / acetonitrile; H2O / 2 h 4.1: LiBr / tetrahydrofuran / 3 h 4.2: 20percent H2SO4 / diethyl ether / 12 h 4.3: 49 percent / K2CO3 / methanol / 3 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 22 p. 7487 - 7495
反应条件
potassium hydroxide in various solvent(s) T=30°C; pH=12; 20 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 347, # 14 p. 1827 - 1834
