(R)-(+)-1,2-环氧辛烷合成路线 （共 27 条）
反应条件
diisopropylammonium hydrogen difluoride T=110°C; 8 h; other optically active epoxides; other HF*amine reagents; var. temperature; var. reaction time; Product distributionMechanism;
参考文献
Umezawa; Takahashi; Furuhashi; Nohira
Tetrahedron Asymmetry, 1993 , vol. 4, # 9 p. 2053 - 2060
反应条件
1: copper(l) chloride / tetrahydrofuran / 3.5 h / -40 °C / |Inert atmosphere 2: 4 h / 0 - 20 °C / |Inert atmosphere 3: ethylene glycol dimethyl ether / 6 h / 40 °C 4: potassium carbonate; dihydrogen peroxide / water; methanol; dimethyl sulfoxide / 1.5 h / 50 - 70 °C 5: acetic acid; methanesulfonic acid / 13 h / 40 - 105 °C View Scheme
参考文献
Hasegawa, Tomoyuki; Kawanaka, Yasufumi; Kasamatsu, Eichi; Ohta, Chisa; Nakabayashi, Kazuhiro; Okamoto, Masaki; Hamano, Masaya; Takahashi, Keiji; Ohuchida, Shuichi; Hamada, Yasumasa
Organic Process Research and Development, 2005 , vol. 9, # 6 p. 774 - 781
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Node, Manabu; Nishide, Kiyoharu; Shigeta, Yukihiro; Obata, Kenichi; Shiraki, Hiroaki; Kunishige, Hideaki
Tetrahedron, 1997 , vol. 53, # 38 p. 12883 - 12894
反应条件
1: 31 percent / organotin phosphate condensates (OPC) / Heating 2: NaI, chlorotrimethylsilane / acetonitrile / Heating View Scheme
参考文献
Otera, Junzo; Niibo, Yoshihisa; Nozaki, Hitosi
Tetrahedron, 1991 , vol. 47, # 36 p. 7625 - 7634
反应条件
1: 41 percent / pyridinium poly(hydrogen fluoride) / diethyl ether / 3 h 2: 71 percent / pyridine / 6 h / Ambient temperature View Scheme
参考文献
Molecular Crystals and Liquid Crystals (1969-1991), , vol. 180, p. 379 - 388
反应条件
1: 31 percent / organotin phosphate condensates (OPC) / Heating
2: NaI, chlorotrimethylsilane / acetonitrile / Heating
View Scheme
参考文献
Otera, Junzo; Niibo, Yoshihisa; Nozaki, Hitosi
Tetrahedron, 1991 , vol. 47, # 36 p. 7625 - 7634
反应条件
pyridine in (2S)-N-methyl-1-phenylpropan-2-amine hydrate
参考文献
Canon Kabushiki Kaisha; Yamakawa Yakuhin Kogyo Kabushiki Kaisha
Patent: US4798680 A1, 1989 ;
