2-氨基-5-异丙基噻唑-4-甲酸乙酯合成路线 （共 2 条）
反应条件
in ethanol
18 h; Heating / reflux;
参考文献
BAYER PHARMACEUTICALS CORPORATION
Patent: WO2006/121904 A1, 2006 ;
Location in patent: Page/Page column 57 ;
反应条件
methanol; sodium
1.) Et2O, 0 deg C, 1 h, 2.) MeOH, reflux, 4 h; Multistep reaction;
参考文献
Barton, Anne; Breukelman, Stephen P.; Kaye, Perry T.; Meakins, G. Denis; Morgan, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 159 - 164
