2-氨基-5-溴嘧啶合成路线

参考文献

Journal of the American Chemical Society, , vol. 68, p. 1039,1040, 1044

7752-82-12-氨基-5-溴嘧啶+

544-92-3氰化亚铜

1753-48-62-氨基嘧啶-5-腈

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 8 p. 1203 - 1208

108-48-52,6-二甲基吡啶+

7752-82-12-氨基-5-溴嘧啶+

75-36-5乙酰氯

180530-15-82-乙酰氨基-5-溴嘧啶

参考文献

Affinium Pharmaceuticals, Inc.
Patent: EP1226138 B1, 2004 ;

7752-82-12-氨基-5-溴嘧啶+

2065-75-02-溴丙二醛

865156-67-86-溴咪唑并[1,2-a]嘧啶-3-甲醛

参考文献

PIRAMAL LIFE SCIENCES LIMITED; KUMAR, Sanjay; HARIHARAN, Sivaramakrishnan; BHONDE, Mandar; DAGIA, Nilesh; SHARMA, Rajiv; MANE, Pallavi Hanmantrao; KUMAR, Pramod Bhaskar
Patent: WO2011/55320 A1, 2011 ;
Location in patent: Page/Page column 50 ;
WO 2011/055320 A1

7752-82-12-氨基-5-溴嘧啶+

100-39-0溴化苄

886366-28-5

参考文献

Lu, Jun; Li, Nan-Sheng; Koo, Selene C.; Piccirilli, Joseph A.
Journal of Organic Chemistry, 2009 , vol. 74, # 21 p. 8021 - 8030

7752-82-12-氨基-5-溴嘧啶+

70-23-53-溴丙酮酸乙酯

907945-69-1

参考文献

Takeda Pharmaceutical Company Limited
Patent: EP1849465 A1, 2007 ;
Location in patent: Page/Page column 88 ;

696-59-32,5-二甲氧基四氢呋喃+

7752-82-12-氨基-5-溴嘧啶

478258-70-7

参考文献

RANBAXY LABORATORIES LIMITED
Patent: WO2006/38100 A1, 2006 ;
Location in patent: Page/Page column 77 ;

7752-82-12-氨基-5-溴嘧啶+

100-52-7苯甲醛

38373-55-62-苄基氨基-5-溴嘧啶

参考文献

Naito et al.
Yakugaku Zasshi, 1952 , vol. 72, p. 348
Chem.Abstr., 1953 , p. 6408