1: 71 percent / dioxane / 1.) 100 min, 2.) reflux, 22 h 2: hydrogen / 10 percent palladium/charcoal / ethanol; H2O / Ambient temperature 3: 32 percent / conc. hydrochloric acid / ethanol; H2O / 2.5 h / Heating 4: 60 percent / 6 N hydrochloric acid / 7.5 h / Heating 5: 27 percent / 10 percent palladium/charcoal / various solvent(s) / 50 h / Heating 6: 71 percent / hydrogen chloride / methanol; pyridine / 0.67 h / 190 °C View Scheme

1: 71 percent / dioxane / 1.) 100 min, 2.) reflux, 22 h 2: hydrogen / 10 percent palladium/charcoal / ethanol; H2O / Ambient temperature 3: 32 percent / conc. hydrochloric acid / ethanol; H2O / 2.5 h / Heating 4: 60 percent / 6 N hydrochloric acid / 7.5 h / Heating 5: 27 percent / 10 percent palladium/charcoal / various solvent(s) / 50 h / Heating View Scheme