乙基2-甲基-4,5,6,7-四氢-1,3-苯并噻唑-5-羧酸酯合成路线 （共 10 条）
反应条件
diethyl ether; sodium
参考文献
Maillard; Delaunay; Langlois; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 451 - 456
反应条件
1: 83 percent / H2 / Ru/C / ethanol / 18 h / 120 °C / 75005.9 Torr
2: 93.5 percent / CrO3, H2SO4 / acetone; H2O / 5 - 10 °C
3: Br2 / diethyl ether / 5 °C
4: 53 percent / dimethylformamide / 16 h / Ambient temperature
View Scheme
参考文献
Maillard; Delaunay; Langlois; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 457 - 460
反应条件
in N,N-dimethyl-formamide
16 h; Ambient temperature;
参考文献
Maillard; Delaunay; Langlois; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 457 - 460
反应条件
1: Br2 / diethyl ether / 5 °C
2: 53 percent / dimethylformamide / 16 h / Ambient temperature
View Scheme
参考文献
Maillard; Delaunay; Langlois; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 457 - 460
反应条件
1: 93.5 percent / CrO3, H2SO4 / acetone; H2O / 5 - 10 °C
2: Br2 / diethyl ether / 5 °C
3: 53 percent / dimethylformamide / 16 h / Ambient temperature
View Scheme
参考文献
Maillard; Delaunay; Langlois; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 457 - 460
反应条件
1: Br2 / diethyl ether / 1 h / 20 °C
2: 57 percent / ethanol
3: 85 percent / Na, Et2O
View Scheme
参考文献
Maillard; Delaunay; Langlois; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 451 - 456
反应条件
1: 57 percent / ethanol
2: 85 percent / Na, Et2O
View Scheme
参考文献
Maillard; Delaunay; Langlois; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 451 - 456
反应条件
lithium aluminium tetrahydride in diethyl ether
35 h; Ambient temperature;
参考文献
Maillard; Delaunay; Langlois; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 457 - 460
反应条件
1: 95 percent / LiAlH4 / diethyl ether / 35 h / Ambient temperature
2: 75 percent / pyridine / 16 h
View Scheme
参考文献
Maillard; Delaunay; Langlois; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 457 - 460
反应条件
1: 95 percent / LiAlH4 / diethyl ether / 35 h / Ambient temperature
2: 75 percent / pyridine / 16 h
3: 77 percent / methanol / 20 h / 90 °C
View Scheme
参考文献
Maillard; Delaunay; Langlois; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 457 - 460
