2-甲基-4-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)苯甲腈合成路线 （共 2 条）
反应条件
potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in ethylene glycol dimethyl ether
T=80°C; 5 h; Inert atmosphere;
参考文献
PFIZER INC.; ARHANCET, Graciela Barbieri; CASIMIRO-GARCIA, Agustin; CHEN, Xiangyang; HEPWORTH, David; MEYERS, Marvin Jay; PIOTROWSKI, David Walter; RAHEJA, Raj Kumar
Patent: WO2010/116282 A1, 2010 ;
Location in patent: Page/Page column 56 ;
WO 2010/116282 A1
反应条件
tert.-butyl lithium in tetrahydrofuran
T=-78°C; 2 h;
参考文献
Schulz, Mark J.; Coats, Steven J.; Hlasta, Dennis J.
Organic Letters, 2004 , vol. 6, # 19 p. 3265 - 3268
