2-甲硫基-4-氨基嘧啶-5-羧酸乙酯合成路线 （共 23 条）
反应条件
potassium hydroxide; water
参考文献
Journal of Organic Chemistry, , vol. 21, p. 567,571
反应条件
in pyridine 1 h; Heating; Product distributionMechanism;
参考文献
Journal of Organic Chemistry, , vol. 46, # 20 p. 3956 - 3959
反应条件
in pyridine 1 h; Heating; Product distributionMechanism;
参考文献
Journal of Organic Chemistry, , vol. 46, # 20 p. 3956 - 3959
反应条件
in pyridine 1 h; Heating; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 46, # 20 p. 3956 - 3959
反应条件
in pyridine 1 h; Heatingother temp. and time; Product distributionMechanism;
参考文献
Journal of Organic Chemistry, , vol. 46, # 20 p. 3956 - 3959
反应条件
in pyridine 1 h; Heating; Product distributionMechanism;
参考文献
Journal of Organic Chemistry, , vol. 46, # 20 p. 3956 - 3959
反应条件
1.1: 76 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 20 °C 2.1: 100 percent / MnO2 / CHCl3 / 20 °C 3.1: 75 percent / tetrahydrofuran / 3 h / Heating 4.1: 45 percent / N,N-diisopropylamine; 1,8-diazabicyclo[5.4.0]undec-7-ene / Heating 5.1: NaH / dimethylformamide / 50 °C 5.2: dimethylformamide / 50 °C 6.1: (+/-)-trans-2-(phenylsulfonyl)-3-phenyloxaziridine / CHCl3 / 20 °C View Scheme
参考文献
Barvian; Boschelli; Cossrow; Dobrusin; Fattaey; Fritsch; Fry; Harvey; Keller; Garrett; La; Leopold; McNamara; Quin; Trumpp-Kallmeyer; Toogood; Wu; Zhang
Journal of Medicinal Chemistry, 2000 , vol. 43, # 24 p. 4606 - 4616
反应条件
1: 98 percent / LAH / tetrahydrofuran / 20 °C 2: 74 percent / MnO2 / CHCl3 3: 88 percent / tetrahydrofuran; diethyl ether 4: 42 percent / 4A molecular sieves; N-methyl morpholine oxide; tetrapropylammonium perruthenate / CH2Cl2 / 20 °C View Scheme
参考文献
VanderWel, Scott N.; Harvey, Patricia J.; McNamara, Dennis J.; Repine, Joseph T.; Keller, Paul R.; Quin III, John; Booth, R. John; Elliott, William L.; Dobrusin, Ellen M.; Fry, David W.; Toogood, Peter L.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2371 - 2387
反应条件
1: 76 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 20 °C 2: 100 percent / MnO2 / CHCl3 / 20 °C 3: 75 percent / tetrahydrofuran / 3 h / Heating 4: 45 percent / N,N-diisopropylamine; 1,8-diazabicyclo[5.4.0]undec-7-ene / Heating View Scheme
参考文献
Barvian; Boschelli; Cossrow; Dobrusin; Fattaey; Fritsch; Fry; Harvey; Keller; Garrett; La; Leopold; McNamara; Quin; Trumpp-Kallmeyer; Toogood; Wu; Zhang
Journal of Medicinal Chemistry, 2000 , vol. 43, # 24 p. 4606 - 4616
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C;
参考文献
VanderWel, Scott N.; Harvey, Patricia J.; McNamara, Dennis J.; Repine, Joseph T.; Keller, Paul R.; Quin III, John; Booth, R. John; Elliott, William L.; Dobrusin, Ellen M.; Fry, David W.; Toogood, Peter L.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2371 - 2387
