3-(2-羧基苯基)丙酸合成路线 （共 67 条）
反应条件
1: bei der Destillation 2: alcoholic water; hydroxylamine hydrochloride View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 275, p. 342
反应条件
1: thionyl chloride / 4 h / 70 - 80 °C 2: potassium carbonate / methanol; water / 2 h / 60 °C 3: oxalyl dichloride / dichloromethane / 1 h / 20 °C 4: sodium azide / water; acetone / 1 h / 0 °C 5: benzene / 1 h / Reflux 6: dichloromethane / 2 h / 20 °C 7: sodium hydride / tetrahydrofuran / 1 h / 0 °C 8: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / benzene / 5 h / 70 °C 9: potassium tert-butylate / tert-butyl alcohol / 0.25 h / 70 - 85 °C View Scheme
参考文献
Muejde, Berk; Oezcan, Sevil; Balci, Metin
Phytochemistry Letters, 2011 , vol. 4, # 4 p. 407 - 410
反应条件
aluminium trichloride; sodium chloride T=160°C; 2 h;
参考文献
Subba Rao; Hariprakasha; Girija; Vijaya Bhaskar
Journal of the Indian Chemical Society, 1997 , vol. 74, # 11-12 p. 961 - 969
参考文献
Wislicenus,J.; Koenig
Justus Liebigs Annalen der Chemie, 1893 , vol. 275, p. 342
反应条件
bei der Destillation;
参考文献
Wislicenus,J.; Koenig
Justus Liebigs Annalen der Chemie, 1893 , vol. 275, p. 342
参考文献
Titley
Journal of the Chemical Society, 1928 , p. 2576
反应条件
1: LiAlH4; diethyl ether 2: N,N-dimethyl-aniline; chloroform; thionyl chloride 3: aq.-ethanolic KOH 4: H2SO4 5: NaH; diethyl ether 6: aqueous HCl; acetic acid View Scheme
参考文献
Page; Tarbell
Journal of the American Chemical Society, 1953 , vol. 75, p. 2053
反应条件
1: bei der Destillation 2: glacial acetic acid; chlorine View Scheme
参考文献
Wislicenus,J.; Koenig
Justus Liebigs Annalen der Chemie, 1893 , vol. 275, p. 342
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Kan, Wai-Ming; Chern, Ching-Yuh; Su, Sheng-Fang
Journal of the Chinese Chemical Society, 1998 , vol. 45, # 6 p. 711 - 712
反应条件
1: 94 percent / conc. H2SO4 / 0.5 h / Ambient temperature
2: 87 percent / LiBH4 / dioxane / 100 °C
3: 78 percent / conc. H2SO4 / 2 h / Heating
View Scheme
参考文献
Zhao, Jin; Dong, Hong-Bo; Yang, Ming-Yan; Du, Juan; Jiang, Jia-Zheng; Wang, Ming-An
Journal of Asian Natural Products Research, 2014 , vol. 16, # 3 p. 312 - 317
