2-氨基-6-(三氟甲基)苯并噻唑合成路线 （共 7 条）
反应条件
sodium iodide dichloride T=70°C; 2 h;
参考文献
Telvekar, Vikas N.; Bachhav, Harshal M.; Bairwa, Vinod Kumar
Synlett, 2012 , vol. 23, # 15 p. 2219 - 2222
反应条件
bromine; acetic acid
参考文献
US2832761 , ;
US2822359 , ;
US2865909 , ;
US2857372 , ;
反应条件
bromine in chloroform 4 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 16 p. 5678 - 5682
反应条件
1: hydrochloric acid / H2O / 4 h / Heating 2: bromine / CHCl3 / 4 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 16 p. 5678 - 5682
反应条件
bromine in acetic acid
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 33, p. 2301 - 2307,2240 - 2245
反应条件
1: With tert.-butylnitrite; copper dichloride in acetonitrile T=20°C; 0.166667 h; 2: 6-trifluoromethyl-2-aminobenzothiazole in acetonitrile T=65°C; 0.5 h; 3: With hydrogenchloride in water; acetonitrile
参考文献
Bayer Pharmaceuticals Corporation
Patent: US2004/224997 A1, 2004 ;
Location in patent: Page 30 ;
反应条件
isopentyl nitrite in tetrahydrofuran 0.5 h; Reflux;
参考文献
Fischer, Georg M.; Klein, Matthias K.; Daltrozzo, Ewald; Zumbusch, Andreas
European Journal of Organic Chemistry, 2011 , # 19 p. 3421 - 3429
