3,4,6-三-O-乙酰基-2-脱氧-2-(1,3-二氧代-1,3-二氢-2H-异吲哚-2-基)己糖吡喃糖苷氯化物合成路线 （共 19 条）
反应条件
1: 1.) HgO, HgCl2, Drierite / 1.) dichloromethane, 1 h, r.t. 2.) 48 h 2: sodium methoxide, methanol / dioxane / 1 h / Ambient temperature View Scheme
参考文献
Alais, Jocelyne; David, Serge
Carbohydrate Research, 1990 , vol. 201, # 1 p. 69 - 77
反应条件
calcium sulfate; mercury dichloride; mercury(II) oxide 1.) dichloromethane, 1 h, r.t. 2.) 48 h; Yield given. Multistep reaction;
参考文献
Alais, Jocelyne; David, Serge
Carbohydrate Research, 1990 , vol. 201, # 1 p. 69 - 77
反应条件
4 A molecular sieve; silver trifluoromethanesulfonate in dichloromethane 24 h; Ambient temperature;
参考文献
Carbohydrate research, , vol. 162, # 2 p. 227 - 235
反应条件
1: 52 percent / AgOSO2CF3, s-collidine / 1,2-dichloro-ethane / 14 h / 20 - 25 °C
2: n-BuNH2 / methanol / 24 h / Heating
3: methanol / 14 h / 20 - 25 °C
4: H2 / 10percent Pd-C / dimethylformamide; H2O / 6 h / 40 °C
View Scheme
参考文献
Ogawa, Tomoya; Nakabayashi, Satoru
Agricultural and Biological Chemistry, 1981 , vol. 45, # 10 p. 2329 - 2336
反应条件
1: 1.) HgO, HgCl2, Drierite / 1.) dichloromethane, 1 h, r.t. 2.) 48 h
2: sodium methoxide, methanol / dioxane / 1 h / Ambient temperature
3: 4-toluenesulfonic acid / acetonitrile / 12 h / Ambient temperature
4: 1.) sodium hydride / 1.) N,N-dimethylformamide, 15 min, 0 deg C 2.) 1 h, 0 deg C; 3 h, r.t.
5: 70 percent / NaBH3CN, 3 Angstroem molecular sieves, HCl / tetrahydrofuran; diethyl ether / 5 h / Ambient temperature
View Scheme
参考文献
Alais, Jocelyne; David, Serge
Carbohydrate Research, 1990 , vol. 201, # 1 p. 69 - 77
反应条件
1: 1.) HgO, HgCl2, Drierite / 1.) dichloromethane, 1 h, r.t. 2.) 48 h
2: sodium methoxide, methanol / dioxane / 1 h / Ambient temperature
3: 4-toluenesulfonic acid / acetonitrile / 12 h / Ambient temperature
4: 1.) sodium hydride / 1.) N,N-dimethylformamide, 15 min, 0 deg C 2.) 1 h, 0 deg C; 3 h, r.t.
View Scheme
参考文献
Alais, Jocelyne; David, Serge
Carbohydrate Research, 1990 , vol. 201, # 1 p. 69 - 77
反应条件
With dichloromethoxy methane; boron trifluoride diethyl etherate in chloroform T=65°C; 3 h; Inert atmosphere; Show Experimental Procedure
参考文献
Bednarczyk, Dorota; Walczewska, Agata; Grzywacz, Daria; Sikorski, Artur; Liberek, Beata; Myszka, Henryk Carbohydrate Research, 2013 , vol. 367, p. 10 - 17
反应条件
Multi-step reaction with 2 steps 1: 79.3 percent / mercury(II) cyanide / nitromethane; toluene / 20 °C / 4 Angstroem molecular sieve2: 90.2 percent / sodium methoxide / methanol / 4 h
参考文献
Charon, Daniel; Mondange, Michelle; Szabo, Ladislas Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 10 p. 2291 - 2296
反应条件
With silver trifluoromethanesulfonate in dichloromethane 18 h; Ambient temperature;
参考文献
Kantoci; Keglevic; Derome Carbohydrate research, 1987 , vol. 162, # 2 p. 227 - 235
