反应条件
1: 95 percent / NaOMe / benzene 2: 1.) Et3N, 2.) aq. KOH / 1.) MeOH, 2.) dioxane 3: 2.) Et3N / 1.) THF, -78 to 0 deg C, 2.) 0-25 deg C 4: NBS / tetrahydrofuran / -78 °C 5: 100 percent / dimethylformamide / 140 °C 6: 92 percent / TMSCl / CH2Cl2 7: 1.) BH3*Me2S, 2.) alkaline H2O2 / 1.) THF 8: 98 percent / Raney Ni, KOH / methanol 9: 81 percent / 1,1'-(azodicarbonyl)dipiperidine, Bu3P 10: 65 percent / NBS, (PhCOO)2 / CCl4 / Heating 11: 79 percent / Li, NH3, t-BuOH / tetrahydrofuran 12: 95 percent / 3 N aq. HCl / 90 °C View Scheme
参考文献
Mulzer, Johann; Duerner, Gerd; Trauner, Dirk
Angewandte Chemie, 1996 , vol. 108, # 23/24 p. 3046 - 3048
