2-(3-溴-4-氟苯基)-1,3-二恶戊环合成路线 （共 6 条）
反应条件
toluene-4-sulfonic acid in water; ethylene glycol; toluene
参考文献
Imperial Chemical Industries PLC
Patent: US5225607 A1, 1993 ;
反应条件
chloro-trimethyl-silane in ice-water; toluene
参考文献
Bayer Aktiengesellschaft
Patent: US4626601 A1, 1986 ;
反应条件
toluene-4-sulfonic acid in water; ethylene glycol; toluene
参考文献
Imperial Chemical Industries PLC
Patent: US4791139 A1, 1988 ;
反应条件
trimethylsilyl trifluoromethanesulfonate in dichloromethane
T=-78°C; Addition; 1 h;
参考文献
Beddie, David G.; Farnham, Andrew W.; Khambay, Bhupinder P. S.
Pesticide Science, 1995 , vol. 44, # 3 p. 261 - 268
反应条件
potassium chloride; phenolated sodium in diethylene glycol dimethyl ether; toluene
参考文献
Bayer Aktiengesellschaft
Patent: US4626601 A1, 1986 ;
反应条件
1-methyl-pyrrolidin-2-one
T=120°C; Ullmann diaryl etherification; 5 h; Inert atmosphere;
参考文献
Mulla, Shafeek A.R.; Inamdar, Suleman M.; Pathan, Mohsinkhan Y.; Chavan, Santosh S.
Tetrahedron Letters, 2012 , vol. 53, # 14 p. 1826 - 1829
