1-异丙基-1,2,3,4-四氢异喹啉合成路线 （共 18 条）
反应条件
sodium tetrahydroborate; trifluoromethanesulphonyl fluoride; tetraethylammonium cyanide
Yield given. Multistep reaction;
参考文献
Richter-Addo, George B.; Knight, D. Andrew; Dewey, Michael A.; Arif, Atta M.; Gladysz
Journal of the American Chemical Society, 1993 , vol. 115, # 25 p. 11863 - 11873
反应条件
O,O'-bistributyltin benzopinacolate in benzene
T=100°C; 3 h;
参考文献
Tomaszewski, Miroslaw J.; Warkentin, John
Journal of the Chemical Society, Chemical Communications, 1993 , # 18 p. 1407 - 1408
反应条件
1: 91 percent / Et3N / diethyl ether / 6 h / Heating
2: 1) n-BuLi / 1) THF, -78 deg C, 1 h; 2) -80 deg C, 2 h, then -20 deg C
3: 83 percent / 2.0 M HCl / 8 h / Heating
View Scheme
参考文献
Seebach, Dieter; Lohmann, Jean-Jacques; Syfrig, Max A.; Yoshifuji, Masaaki
Tetrahedron, 1983 , vol. 39, # 12 p. 1963 - 1974
反应条件
1: NaAlH2(OCH2CH2OCH3)2 / tetrahydrofuran / 7 h / 0 - 5 °C / further solvent, varying concentration, temperature and reaction time
2: 91 percent / Et3N / diethyl ether / 6 h / Heating
3: 1) n-BuLi / 1) THF, -78 deg C, 1 h; 2) -80 deg C, 2 h, then -20 deg C
4: 83 percent / 2.0 M HCl / 8 h / Heating
View Scheme
参考文献
Seebach, Dieter; Lohmann, Jean-Jacques; Syfrig, Max A.; Yoshifuji, Masaaki
Tetrahedron, 1983 , vol. 39, # 12 p. 1963 - 1974
反应条件
in sulfuric acid
electroreduction on Pb;
参考文献
Ferles, Miloslav; Sputova, Michaela; Tegza, Marian
Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 1 p. 262 - 265
反应条件
1.1: LDA / tetrahydrofuran / -78 °C
1.2: tetrahydrofuran
2.1: hydrazine hydrate; glacial acetic acid / 60 °C
View Scheme
参考文献
Singh, Kamal Nain; Singh, Paramjit; Kaur, Amarjit
Synthetic Communications, 2006 , vol. 36, # 22 p. 3339 - 3343
反应条件
1: 1) n-BuLi / 1) THF, -78 deg C, 1 h; 2) -80 deg C, 2 h, then -20 deg C
2: 83 percent / 2.0 M HCl / 8 h / Heating
View Scheme
参考文献
Seebach, Dieter; Lohmann, Jean-Jacques; Syfrig, Max A.; Yoshifuji, Masaaki
Tetrahedron, 1983 , vol. 39, # 12 p. 1963 - 1974
反应条件
Yield given. Multistep reaction;
参考文献
Katritzky, Alan R.; Akutagawa, Kunihiko
Tetrahedron, 1986 , vol. 42, # 9 p. 2571 - 2574
