2,3-二氢-4(1H)-菲酮合成路线 （共 49 条）
反应条件
1: H+, molecular sieves View Scheme
参考文献
Journal of Chemical Thermodynamics, , vol. 21, # 2 p. 179 - 202
反应条件
trifluorormethanesulfonic acid CH2Cl2, -78 deg C -> room temp., overnight; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 49, # 1 p. 207 - 209
反应条件
1: 1.) Mg / 1.) Et2O, 2.) Et2O, r.t., 2 d 2: 1.) 9-BBN, 2.) 30percent aq. H2O2, 6 M aq. NaOH / 1.) THF, r.t., 1 h, 2.) EtOH, r.t., 15 min; 50 deg C, 10 min 3: 68 percent / PCC / CH2Cl2 / 7 h / Ambient temperature 4: 4 percent / n-Bu3SnH, AIBN / benzene / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 25 p. 7876 - 7888
反应条件
1: 67 percent / NBS, benzoyl peroxide / CCl4 / 2 h / Heating 2: 1.) Mg / 1.) Et2O, 2.) Et2O, r.t., 2 d 3: 1.) 9-BBN, 2.) 30percent aq. H2O2, 6 M aq. NaOH / 1.) THF, r.t., 1 h, 2.) EtOH, r.t., 15 min; 50 deg C, 10 min 4: 68 percent / PCC / CH2Cl2 / 7 h / Ambient temperature 5: 4 percent / n-Bu3SnH, AIBN / benzene / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 25 p. 7876 - 7888
反应条件
1: 1.) 9-BBN, 2.) 30percent aq. H2O2, 6 M aq. NaOH / 1.) THF, r.t., 1 h, 2.) EtOH, r.t., 15 min; 50 deg C, 10 min 2: 68 percent / PCC / CH2Cl2 / 7 h / Ambient temperature 3: 4 percent / n-Bu3SnH, AIBN / benzene / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 25 p. 7876 - 7888
反应条件
1: 68 percent / PCC / CH2Cl2 / 7 h / Ambient temperature 2: 4 percent / n-Bu3SnH, AIBN / benzene / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 25 p. 7876 - 7888
反应条件
1: AlCl3 / benzene 2: N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether / Heating 3: H2SO4 4: Pd-C / Heating 5: (saponification) 6: (i) SOCl2, Py, Et2O, (ii) SnCl4, benzene View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 2606 - 2609
反应条件
1: (saponification) 2: (i) SOCl2, Py, Et2O, (ii) SnCl4, benzene View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 2606 - 2609
反应条件
1: Pd-C / Heating 2: (saponification) 3: (i) SOCl2, Py, Et2O, (ii) SnCl4, benzene View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 2606 - 2609
反应条件
1: H2SO4 2: Pd-C / Heating 3: (saponification) 4: (i) SOCl2, Py, Et2O, (ii) SnCl4, benzene View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 2606 - 2609
