4-氰基-3-硝基三氟甲基苯合成路线 （共 30 条）
反应条件
potassium phosphate; tetrakis(triphenylphosphine) palladium(0); triphenylphosphine in tetrahydrofuran T=50°C; 24 h;
参考文献
Jiang, Biao; Kan, Ying; Zhang, Ao
Tetrahedron, 2001 , vol. 57, # 8 p. 1581 - 1584
反应条件
T=130°C; 6 h; Product distribution / selectivity;
参考文献
Bayer CropScience S.A.
Patent: US6635780 B1, 2003 ;
Location in patent: Page/Page column 9-10 ;
反应条件
tetra-n-butylammonium tetrafluoroborate in N,N-dimethyl-formamide Electrolysis;
参考文献
Gallardo, Iluminada
Chemistry - A European Journal, 2001 , vol. 7, # 8 p. 1759 - 1765
反应条件
1: ammonia / ethanol / 120 °C 2: 1.) sodium nitrite / 1.) glacial acetic acid, concd. sulfuric acid, 10 to 20 deg C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 43, # 2 p. 311 - 319
反应条件
1: hydroxylamine hydrochloride / dimethyl sulfoxide / 90 °C 2: hydroxylamine hydrochloride; dimethyl sulfoxide / 90 °C View Scheme
参考文献
Synlett, , # 15 art. no. D12411ST, p. 2223 - 2227
反应条件
hydroxylamine hydrochloride; dimethyl sulfoxide T=90°C;
参考文献
Synlett, , # 15 art. no. D12411ST, p. 2223 - 2227
反应条件
sodium nitrite 1.) glacial acetic acid, concd. sulfuric acid, 10 to 20 deg C; Yield given. Multistep reaction;
参考文献
Australian Journal of Chemistry, , vol. 43, # 2 p. 311 - 319
反应条件
(i) NaNO2, H2SO4, (ii) aq. ZnCl2, (iii) /BRN= 3587243/, CuCN, aq. NaHCO3; Multistep reaction;
参考文献
Helvetica Chimica Acta, , vol. 45, p. 2226 - 2241
反应条件
hydrogen bromide Inert atmosphere;
参考文献
Suez, Gal; Bloch, Victoria; Nisnevich, Gennady; Gandelman, Mark
European Journal of Organic Chemistry, 2012 , # 11 p. 2118 - 2122
反应条件
sulfuric acid; water 3 h; Heating / reflux;
参考文献
TIBOTEC PHARMACEUTICALS LTD.; MEDIVIR AB
Patent: WO2007/14922 A1, 2007 ;
Location in patent: Page/Page column 81 ;
